This would be fine to ignore as normally I believe it's supposed to be empty and more or less abandoned. I can't give more details than that as I don't use RLS anymore, but a prime example was the Thalmor HQ in Solitude which became dark as a cave with RLS. There are a few visual conflicts in some instances with RLS, where RLS modifies ambient light sources while this mod assumes vanilla ambient light sources. I've been using as part of an expanded load order based off STEP 2.0 (core only) and there are no conflicts that needs to be resolved in 圎dit, when sorted correctly. If you decide to incorporate it into the guide later on, you should be able to ask the LOOT team to add a metarule so that manual configuration is no longer necessary. If that's still the case today, you can create a custom LOOT rule, to group it into the 'Interior Lighting' group, which puts it at the end of the load order right before RWT, like so: Because of the edits it makes, it needs to be very high priority, so very low in the load order, like RWT and ACMoS.
At the time I installed it, about 6 months ago, it wasn't 'known' to LOOT and its main plugin would be sorted incorrectly in the middle.